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Identifying the risk of dementia from anticholinergic drugs

Dementia is a profound and growing burden on society. Almost one million people live with the disease in the UK, with the impact felt by many more carers and families. The economic cost is estimated to be £23 billion per year and is expected to grow significantly. As there are no preventative treatments to stop this growth, it is vital to understand the risk factors contributing to the disease onset. 

Other illnesses and lifestyle factors are known to influence the risk of dementia. However, researchers are also considering the impact of certain medications. Anticholinergic drugs are commonly prescribed for several medical conditions, such as Parkinson’s disease, overactive bladder, and depression. 

Previous research indicated that anticholinergics could increase the risk of dementia, but these studies were typically small or did not account for how long someone was taking the medication.

Read more of this case study

 

Links:

School for Primary Care Research Project No. 265

PI: Carol Coupland

DOI: